Diabetes, microvascular complications, and cardiovascular complications: what is it about glucose?
نویسندگان
چکیده
منابع مشابه
Diabetes, microvascular complications, and cardiovascular complications: what is it about glucose?
Glycemic control is the primary mediator of diabetic microvascular complications and also contributes to macrovascular complications. A new study (see related article beginning on page 1049) reveals a previously unrecognized association between oxidant activation of poly(ADP ribose) polymerase (PARP) and upregulation of known mediators of glycemic injury. Inhibitors of PARP may have potential t...
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Diabetes is a group of chronic diseases characterized by hyperglycemia. Chronic hyperglycemia injures the human body in many different ways. Modern medical care therefore uses a vast array of lifestyle and pharmaceutical interventions aimed at preventing and controlling hyperglycemia. One of the chief injuries arising from hyperglycemia is injury to vasculature, which is classified as either sm...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2003
ISSN: 0021-9738
DOI: 10.1172/jci200319902